Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 18/20 | 0.54 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | AQP1 | P29972 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891976 | 0.86 | VCP (0.52) | VCP | |
| SCHEMBL8901221 | 0.86 | DCPS (0.51) | VCPDCPSALDH1A1ADRA2AMAPT | |
| SCHEMBL8891551 | 0.84 | VCP (0.54) | VCPALDH1A1ADRA2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL8899106 | 0.84 | VCP (0.53) | VCPALDH1A1ADRA2AMAPTHPGD | |
| SCHEMBL2636279 | 0.80 | NPY5R (0.61) | VCPALDH1A1ADRA2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL2675355 | 0.79 | NPY5R (0.60) | VCPALDH1A1ADRA2AMAPTHPGD | |
| SCHEMBL8900961 | 0.78 | VCP (0.56) | VCPNPY5R | |
| SCHEMBL8900056 | 0.77 | VCP (0.46) | VCPALDH1A1ADRA2AMAPTHPGD | |
| SCHEMBL8898270 | 0.74 | VCP (0.54) | VCPNPY5R | |
| SCHEMBL8892672 | 0.74 | NPY5R (0.56) | VCPALDH1A1ADRA2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |