Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8900980 | 0.95 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8899035 | 0.89 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28624268 | 0.84 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL336350 | 0.84 | TSHR (0.75) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8899370 | 0.83 | ATM (0.43) | TSHRALDH1A1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL10286925 | 0.83 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL4393993 | 0.82 | TSHR (0.79) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29035619 | 0.82 | TSHR (0.79) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL29035560 | 0.82 | TSHR (0.79) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL81413 | 0.81 | TSHR (0.55) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700874-A | CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE | BRIDGESTONE CORPORATION (JP) | 1997-12-23 | — | — | US | disclosed |