Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 6/20 | 0.34 |
| ▸ | TCF4 | P15884 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907639 | 0.84 | CTH (0.38) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8901643 | 0.83 | NQO1 (0.33) | — | |
| SCHEMBL8587198 | 0.81 | TCF4 (0.39) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8900228 | 0.81 | TCF4 (0.39) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8902030 | 0.77 | TCF4 (0.38) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8901605 | 0.77 | TCF4 (0.38) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8533356 | 0.68 | TCF4 (0.38) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8899885 | 0.68 | AKT1 (0.40) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL8899620 | 0.66 | AKT1 (0.50) | CTHAKT1TCF4CTNNB1IDO1 | |
| SCHEMBL1345358 | 0.64 | POLB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606037-A | Processes antineoplastic heteronaphthoquinones | BIOCHEM PHARMA INC. (CA) | 1997-02-25 | — | — | US | disclosed |