SCHEMBL8901363

SCHEMBL8901363

O=C(Cl)c1ccc2c3cccc4c(C(=O)Cl)ccc(c5cccc1c52)c43

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
KDM4E B2RXH2 6/20 0.40
HPGD P15428 4/20 0.40
ALOX15 P16050 1/20 0.40
GAA P10253 2/20 0.39
TSHR P16473 1/20 0.39
TYMS P04818 1/20 0.39
KMT2A Q03164 4/20 0.37
POLB P06746 3/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 2/20 0.37
HSD17B10 Q99714 2/20 0.37
GLA P06280 1/20 0.37
ATM Q13315 1/20 0.35
MAPT P10636 3/20 0.35
CAMKK1 Q8N5S9 2/20 0.35
CAMKK2 Q96RR4 2/20 0.35
MEN1 O00255 2/20 0.35
CYP2C9 P11712 1/20 0.35
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29820418 1.00 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDALOX15GAA
SCHEMBL14003696 0.87 ESR2 (0.38) ALDH1A1KDM4EHPGDALOX15GAA
SCHEMBL6069647 0.87 KMT2A (0.43) ALDH1A1KDM4EHPGDALOX15GAA
SCHEMBL9930840 0.82 CYP1A2 (0.49) ALDH1A1KDM4EHPGDGAATSHR
SCHEMBL3036869 0.81 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDALOX15TSHR
SCHEMBL31139592 0.81 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDALOX15TSHR
SCHEMBL29599305 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDALOX15TSHR
SCHEMBL2154872 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDALOX15TSHR
SCHEMBL2153429 0.80 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDALOX15TSHR
SCHEMBL21849886 0.79 TYMS (0.50) ALDH1A1KDM4EHPGDALOX15GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN claimed
CN-114957156-A Compound containing benzoxazine structure, resin composition, prepreg and electric copper clad laminate, and preparation method and application thereof 成都科宜高分子科技有限公司 2022-08-30 CN disclosed
US-5700897-A Method for making fluorescent polymers OPTICAL SENSORS INCORPORATED (US) 1997-12-23 US disclosed
US-5480723-A Surface-bound fluorescent polymers and related methods of synthesis and use OPTICAL SENSORS INCORPORATED (US) 1996-01-02 US disclosed
US-5354825-A Surface-bound fluorescent polymers and related methods of synthesis and use KLAINER STANLEY M (US) 1994-10-11 US disclosed
WO-1988005533-A1 AMPLIFICATION OF SIGNALS FROM OPTICAL FIBERS KELSIUS, INC. (US) 1988-07-28 WO disclosed