Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631674 | 0.80 | KDM4E (0.46) | KDM4E | |
| SCHEMBL5748851 | 0.79 | LCK (0.52) | KDM4E | |
| SCHEMBL8891123 | 0.79 | CYP2A6 (0.55) | KDM4E | |
| SCHEMBL6606896 | 0.78 | PLAU (0.57) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8890461 | 0.78 | LCK (0.50) | HDAC1KDM4E | |
| SCHEMBL31305702 | 0.76 | HDAC1 (0.71) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6010034 | 0.76 | HDAC1 (0.71) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL3483347 | 0.73 | KDM4E (0.50) | KDM4E | |
| SCHEMBL5748538 | 0.72 | LCK (0.58) | KDM4E | |
| SCHEMBL5746516 | 0.72 | LCK (0.58) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |