Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.71 |
| ▸ | CES2 | O00748 | 1/20 | 0.63 |
| ▸ | CES1 | P23141 | 1/20 | 0.63 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305702 | 1.00 | HDAC1 (0.71) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL10362855 | 0.94 | HDAC8 (0.64) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL27641548 | 0.86 | HDAC3 (0.63) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL10361604 | 0.85 | ALDH1A1 (0.64) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL10361606 | 0.85 | HDAC1 (0.59) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL10207296 | 0.84 | HDAC6 (1.00) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL10362071 | 0.82 | HDAC8 (0.58) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL3031316 | 0.82 | HDAC2 (0.74) | HDAC1HDAC8HDAC2HDAC6DEGS1 | |
| SCHEMBL2405077 | 0.82 | MMP9 (0.58) | HDAC1HDAC8HDAC3HDAC7HDAC2 | |
| SCHEMBL2412199 | 0.82 | HDAC1 (0.75) | HDAC1HDAC8HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038330-A1 | Chemical Compositions and Methodology to Enhance Plant Growth and Development | MCDANIEL ROBERT GENE (US) | 2015-02-05 | — | — | US | claimed |
| US-10478829-B2 | Collector compositions and methods of using same in mineral flotation processes | CYTEC INDUSTRIES INC. (US) | 2019-11-19 | — | — | US | disclosed |
| CN-108603040-A | Method for manufacturing azo pigments | 福禄公司 | 2018-09-28 | — | — | CN | disclosed |
| WO-2017091552-A1 | COLLECTOR COMPOSITIONS AND METHODS OF USING SAME IN MINERAL FLOTATION PROCESSES | CYTEC INDUSTRIES INC. (US) | 2017-06-01 | — | — | WO | disclosed |
| US-20170144168-A1 | COLLECTOR COMPOSITIONS AND METHODS OF USING SAME IN MINERAL FLOTATION PROCESSES | CYTEC INDUSTRIES INC. (US) | 2017-05-25 | — | — | US | disclosed |
| US-9538759-B2 | Chemical compositions and methodology to enhance plant growth and development | MCDANIEL ROBERT GENE (US) | 2017-01-10 | — | — | US | disclosed |
| CN-103351706-B | Jetted ink and its preparation method | 卡伯特公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-102656239-B | Ink jet ink, ink cartridge, and ink jet recording method | CANON KABUSHIKI KAISHA (JP) | 2016-05-18 | — | — | CN | disclosed |
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | KATTAR SOLOMON | 2010-08-26 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| WO-2009045385-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-7030261-B2 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO | 2005-09-01 | — | — | US | disclosed |
| EP-1564206-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-1517884-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | AstraZeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| US-6790644-B2 | ISOLATED FROM ACINETOBACTER JOHNSONII, WHICH DECONTAMINATES/ METABOLIZES ACETYLACETONE | BIOCATALYTICS, INC. | 2004-09-14 | — | — | US | disclosed |
| WO-2004000792-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
| US-20030148487-A1 | 1,3-dicarbonyl-dioxygenase - a new c-c-bond cleaving enzyme | CODEXIS, INC. | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216796-A1 | N-HYDROXY-NAPHTHALENE DICARBOXAMIDE AND N-HYDROXY-BIPHENYL-DICARBOXAMIDE COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | BRDT, AADAC, ACIN1 | HDAC1 5/4885HDAC8 7/4885HDAC3 8/4885 |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | HELZ, MMEL1, GAA | HDAC1 28/4885HDAC8 100/4885HDAC3 157/4885 |
| US-20030148487-A1 | 1,3-dicarbonyl-dioxygenase - a new c-c-bond cleaving enzyme | ALDH7A1, CMBL, DDO | HDAC1 2556/4885HDAC8 3537/4885HDAC3 1985/4885 |
| US-20050192442-A1 | Method for preparing 2-hydroxy-6-ureidocarbonyl naphthalene derivative | HPD, UGDH, HAAO | HDAC1 3194/4885HDAC8 2289/4885HDAC3 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.