Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631674 | 0.92 | KDM4E (0.46) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| Water SCHEMBL29163663 | 0.83 | KDM4E (0.65) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| SCHEMBL15711096 | 0.83 | CYP2A6 (0.50) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5748794 | 0.83 | LCK (0.56) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL5553792 | 0.82 | RAB9A (0.60) | ALDH1A1HPGDMEN1KMT2APOLB | |
| SCHEMBL29594563 | 0.81 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| SCHEMBL18758 | 0.81 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| SCHEMBL6916181 | 0.81 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| SCHEMBL29359975 | 0.81 | KDM4E (0.68) | KDM4EPTPN1ALDH1A1HPGDENPP2 | |
| SCHEMBL7790677 | 0.80 | CES2 (0.36) | KDM4EPTPN1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | GENELABS TECHNOLOGIES, INC. | 2005-08-25 | — | — | US | claimed |
| US-6583133-B1 | Especially against Gram-positive organisms, e.g. methicillin-sensitive (MSSA) and methicillin- resistant (MRSA) staphylococci, enterococci and pneumococci | BASILEA PHARMACEUTICA AG (CH) | 2003-06-24 | — | — | US | claimed |
| EP-1090013-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | claimed |
| WO-2000032605-A1 | BI-PYRROLIDINYLVINL (CARBA) CEPHALOSPORINS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-08 | — | — | WO | claimed |
| WO-1999067255-A1 | PROPENYL CEPHALOSPORIN DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-12-29 | — | — | WO | claimed |
| EP-0745719-A2 | Use of carbohydrate compounds as auxiliary agents in the dyeing or printing of fibrous materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-04 | — | — | EP | claimed |
| US-5281263-A | Disazo dyes for inks printed paper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | claimed |
| EP-2824101-B1 | NOVEL COMPOUND, AND SUPPORT MATERIAL HAVING SAID NOVEL COMPOUND SUPPORTED THEREON | ADEKA CORP (JP) | 2018-05-09 | — | — | EP | disclosed |
| CN-106572659-A | Noxious arthropod control agent containing amide compound | 住友化学株式会社 | 2017-04-19 | — | — | CN | disclosed |
| US-9496095-B2 | Compound and carrier system having the compound | ADEKA CORPORATION (JP) | 2016-11-15 | — | — | US | disclosed |
| US-9006225-B2 | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORPORATION (JP) | 2015-04-14 | — | — | US | disclosed |
| EP-2824101-A1 | NOVEL COMPOUND, AND SUPPORT MATERIAL HAVING SAID NOVEL COMPOUND SUPPORTED THEREON | Adeka Corporation (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-20140353553-A1 | NOVEL COMPOUND AND CARRIER SYSTEM HAVING THE COMPOUND | ADEKA CORPORATION (JP) | 2014-12-04 | — | — | US | disclosed |
| EP-0559310-B1 | Ink compositions | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995031505-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-11-23 | — | — | WO | disclosed |
| US-5383960-A | Ink jet printing inks | ZENECA LIMITED (GB) | 1995-01-24 | — | — | US | disclosed |
| US-5281263-A | Disazo dyes for inks printed paper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0572419-A1 | ANIONIC DISAZO DYES. | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0559310-A1 | Ink compositions | ZENECA LIMITED (GB) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992013037-A1 | ANIONIC DISAZO DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | HAVCR2, MAVS, ZC3HAV1 | KDM4E 2491/4885PTPN1 4660/4885ALDH1A1 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.