Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797473 | 0.89 | GAA (0.59) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL1720494 | 0.85 | MAPT (0.72) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL3499191 | 0.81 | MAPT (0.62) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL3497278 | 0.81 | MAPT (0.66) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL3497274 | 0.80 | MAPT (0.64) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL561797 | 0.78 | TP53 (0.67) | MAPTALDH1A1POLBHTTL3MBTL1 | |
| SCHEMBL900124 | 0.77 | MAPT (0.70) | MAPTALDH1A1POLBGAACYP3A4 | |
| SCHEMBL5885563 | 0.77 | MAPT (0.70) | MAPTALDH1A1POLBGAACYP3A4 | |
| SCHEMBL27417579 | 0.77 | GAA (0.69) | MAPTALDH1A1GAAHTTL3MBTL1 | |
| SCHEMBL337418 | 0.77 | ALDH1A1 (0.65) | MAPTALDH1A1POLBGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693807-A | Substituted hydroquinone derivatives | CIBA-GEIGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5290939-A | Process for the manufacture of brofaromine and analogs thereof | CIBA-GEIGY CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |