Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580374 | 0.89 | ACHE (0.69) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL2720515 | 0.81 | ACHE (0.62) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL4392851 | 0.81 | ACHE (0.62) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL12442621 | 0.81 | ACHE (0.62) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL5871923 | 0.81 | ACHE (0.62) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL2997818 | 0.79 | ACHE (0.60) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL8919161 | 0.79 | SLC18A3 (0.62) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL2130912 | 0.79 | ACHE (0.60) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL18166097 | 0.79 | ACHE (0.81) | ACHEEPHX1L3MBTL3L3MBTL1HPGD | |
| SCHEMBL433828 | 0.79 | ACHE (0.81) | ACHEEPHX1L3MBTL3L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042539-C | 11,21-bisphenyl-19-norpregnane derivatives | AKZO NOBEL NV (NL) | 1999-03-17 | — | — | CN | disclosed |
| EP-0683172-B1 | 11,21-Bisphenyl-19-norpregnane derivatives | AKZO NOBEL NV (NL) | 1997-08-13 | — | — | EP | disclosed |
| US-5620966-A | ANTIGLUOCORTICOID ACTIVITY | AKZO NOBEL N.V. (NL) | 1997-04-15 | — | — | US | disclosed |
| EP-0683172-A1 | 11,21-Bisphenyl-19-norpregnane derivatives | Akzo Nobel N.V. (NL) | 1995-11-22 | — | — | EP | disclosed |