Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360681 | 0.87 | CHRNB2 (0.62) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8476630 | 0.85 | SLC18A3 (0.58) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL5871923 | 0.84 | ACHE (0.62) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL2720515 | 0.84 | ACHE (0.62) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL12442621 | 0.84 | ACHE (0.62) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8472183 | 0.83 | SLC18A3 (0.55) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8475449 | 0.82 | SLC18A3 (0.54) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8474593 | 0.82 | SLC18A3 (0.54) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL4392851 | 0.81 | ACHE (0.62) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 | |
| SCHEMBL8477067 | 0.81 | SLC18A3 (0.53) | SLC18A3ACHEEPHX1L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616750-A | Compounds and process | SMITHKLINE BEECHAM PLC (GB) | 1997-04-01 | — | — | US | disclosed |
| EP-0655950-B1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1996-10-23 | — | — | EP | disclosed |
| EP-0655950-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY. | SMITHKLINE BEECHAM PLC (GB) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994003271-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | SMITHKLINE BEECHAM PLC (GB) | 1994-02-17 | — | — | WO | disclosed |