Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 9/20 | 0.68 |
| ▸ | KDM1A | O60341 | 3/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8913197 | 0.99 | NPY5R (0.67) | NPY5RKDM1AABCG2SLC2A1NPC1 | |
| SCHEMBL8889905 | 0.90 | NPY5R (0.63) | NPY5RKDM1AABCG2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8892216 | 0.89 | HTT (0.64) | NPY5RKDM1AABCG2NPC1RAB9A | |
| SCHEMBL8908702 | 0.88 | NPY5R (0.74) | NPY5RKDM1ANPC1PKMRAB9A | |
| Hydrochloric Acid SCHEMBL8900394 | 0.86 | NPY5R (0.72) | NPY5RKDM1ASLC2A1NPC1PKM | |
| SCHEMBL8893267 | 0.85 | NPY5R (0.60) | NPY5RKDM1ASLC2A1NPC1PKM | |
| Hydrochloric Acid SCHEMBL8909035 | 0.84 | NPY5R (0.59) | NPY5RKDM1ASLC2A1NPC1PKM | |
| SCHEMBL2591063 | 0.83 | NPY5R (1.00) | NPY5RABCG2SLC2A1NPC1PKM | |
| SCHEMBL8890735 | 0.82 | EGFR (0.63) | NPY5RKDM1AABCG2NPC1PKM | |
| Hydrochloric Acid SCHEMBL6039677 | 0.81 | NPY5R (0.96) | NPY5RABCG2SLC2A1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |