Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477067 | 0.89 | SLC18A3 (0.53) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL8472183 | 0.86 | SLC18A3 (0.55) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL8474593 | 0.84 | SLC18A3 (0.54) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL8919161 | 0.81 | SLC18A3 (0.62) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL8476630 | 0.80 | SLC18A3 (0.58) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL7364546 | 0.78 | HDAC3 (0.64) | ACHEEPHX1L3MBTL3L3MBTL1HSD11B1 | |
| SCHEMBL5871923 | 0.76 | ACHE (0.62) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL4392851 | 0.76 | ACHE (0.62) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL2720515 | 0.76 | ACHE (0.62) | SLC18A3ACHENPC1RAB9AATM | |
| SCHEMBL12442621 | 0.76 | ACHE (0.62) | SLC18A3ACHENPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997040010-A1 | HALOGENATED NAPHTHYL METHOXY PIPERIDINES FOR MAPPING SEROTONIN TRANSPORTER SITES | EMORY UNIVERSITY (US) | 1997-10-30 | — | — | WO | disclosed |