Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.72 |
| ▸ | PDE5A | O76074 | 3/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8891614 | 0.98 | NPY5R (0.70) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL30960995 | 0.91 | NPY5R (0.66) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL2257238 | 0.91 | NPY5R (0.66) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL27610153 | 0.87 | ABCG2 (0.67) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL2231403 | 0.87 | NPY5R (0.68) | NPY5RPDE5AABCG2MAPTMEN1 | |
| Ether SCHEMBL8905875 | 0.85 | NPY5R (0.55) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL8892229 | 0.85 | NPY5R (0.97) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL3121675 | 0.85 | ALDH1A1 (0.66) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL3119082 | 0.84 | KDR (0.63) | NPY5RPDE5AABCG2MAPTMEN1 | |
| SCHEMBL8890555 | 0.84 | NPY5R (1.00) | NPY5RPDE5AABCG2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020821-A1 | HETEROARYL DERIVATIVES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |