Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | PDE5A | O76074 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890555 | 0.98 | NPY5R (1.00) | NPY5RMAPTPDE5AABCG2KDM4E | |
| Hydrochloric Acid SCHEMBL8890165 | 0.98 | NPY5R (0.94) | NPY5RMAPTPDE5AABCG2KDM4E | |
| Hydrochloric Acid SCHEMBL8901136 | 0.97 | NPY5R (0.97) | NPY5RMAPTPDE5AABCG2KDM4E | |
| SCHEMBL2587936 | 0.90 | NPY5R (0.84) | NPY5RMAPTPDE5AABCG2KDM4E | |
| SCHEMBL2591063 | 0.88 | NPY5R (1.00) | NPY5RPDE5AABCG2MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL6039677 | 0.86 | NPY5R (0.96) | NPY5RMAPTPDE5AABCG2KDM4E | |
| SCHEMBL8901627 | 0.85 | NPY5R (0.72) | NPY5RMAPTPDE5AABCG2KDM4E | |
| SCHEMBL2590759 | 0.85 | NPY5R (0.76) | NPY5RMAPTPDE5AABCG2KDM4E | |
| SCHEMBL12176298 | 0.84 | SLC2A1 (0.72) | NPY5RMAPTPDE5AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7549537 | 0.84 | NPY5R (0.79) | NPY5RMAPTPDE5AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020822-A1 | QUINAZOLIN-2,4-DIAZIRINES AS NPY RECEPTOR ANTAGONIST | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | claimed |