Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8916314 | 1.00 | HRH4 (0.31) | HRH4HRH3DPP8DPP7CRHR1 | |
| Trifluoroacetic Acid SCHEMBL8901689 | 0.81 | PLG (0.42) | DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL8916303 | 0.81 | PLG (0.42) | DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL8892655 | 0.76 | NPC1 (0.40) | HRH4HRH3CRHR1 | |
| Trifluoroacetic Acid SCHEMBL29936279 | 0.73 | PDK1 (0.39) | HRH4HRH3DPP8 | |
| Trifluoroacetic Acid SCHEMBL27702554 | 0.73 | PDK1 (0.43) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL28847772 | 0.71 | DPP8 (0.36) | HRH4HRH3DPP8DPP7 | |
| SCHEMBL5210176 | 0.70 | — | — | |
| SCHEMBL2045009 | 0.70 | — | — | |
| Trifluoroacetic Acid SCHEMBL27731525 | 0.68 | EPHX1 (0.45) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |