Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28847772

CCC1CCC(NC)C1.NC=O.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL28163208 0.86 ADH1B (0.33)
Trifluoroacetic Acid SCHEMBL4855744 0.82 DPP8 (0.39) DPP8DPP7
SCHEMBL25152712 0.76
SCHEMBL12599507 0.76
Trifluoroacetic Acid SCHEMBL16324366 0.72 FASN (0.40) DPP8HRH4HRH3
Trifluoroacetic Acid SCHEMBL8916314 0.71 HRH4 (0.31) DPP8DPP7HRH4HRH3
Trifluoroacetic Acid SCHEMBL15717492 0.71 RXFP1 (0.34) DPP7HRH4HRH3
Trifluoroacetic Acid SCHEMBL8901701 0.71 HRH4 (0.31) DPP8DPP7HRH4HRH3
SCHEMBL4855748 0.70
SCHEMBL3615764 0.69 ADH1B (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104797553-B 3 aminocyclopentanecarasxamides derivatives 默克专利股份公司 2017-07-21 CN disclosed