Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902364 | 0.86 | CDK1 (0.52) | PTGS2CTSSCTSKPTGS1 | |
| SCHEMBL8903318 | 0.85 | CDK1 (0.53) | PTGS2CTSSCTSKADORA3ADORA1 | |
| SCHEMBL8902849 | 0.84 | CA1 (0.43) | PTGS2CTSSCTSKADORA3CA1 | |
| SCHEMBL8902911 | 0.83 | CDK1 (0.55) | PTGS2CTSSCTSKADORA3PTGS1 | |
| SCHEMBL8901655 | 0.83 | CDK1 (0.55) | PTGS2CTSSCTSKADORA3PTGS1 | |
| SCHEMBL8903387 | 0.81 | CDK1 (0.39) | PTGS2CTSSCTSKADORA3 | |
| SCHEMBL8902502 | 0.81 | CDK1 (0.55) | CTSSCTSKADORA3ADORA1 | |
| SCHEMBL8901819 | 0.80 | PTGS2 (0.46) | PTGS2CA1CA2PTGS1 | |
| SCHEMBL8903452 | 0.80 | CDK1 (0.41) | PTGS2CTSSCTSKADORA3 | |
| SCHEMBL8903186 | 0.80 | CDK1 (0.41) | PTGS2CTSSCTSKADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0675124-A2 | Purine derivatives and suppressants for inflammatory diseases | JAPAN ENERGY CORPORATION (JP) | 1995-10-04 | — | — | EP | disclosed |