Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.55 |
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.55 |
| ▸ | MGMT | P16455 | 5/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902364 | 0.85 | CDK1 (0.52) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8903318 | 0.84 | CDK1 (0.53) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8902498 | 0.84 | CDK1 (0.38) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8903387 | 0.83 | CDK1 (0.39) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8901655 | 0.82 | CDK1 (0.55) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8902911 | 0.82 | CDK1 (0.55) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8903186 | 0.81 | CDK1 (0.41) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8901822 | 0.81 | PTGS2 (0.46) | ADORA3ADORA1CTSSCTSK | |
| SCHEMBL8903379 | 0.80 | PIN1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8902849 | 0.75 | CA1 (0.43) | ADORA3ADORA1ADORA2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | claimed |
| US-5602140-A | CAUSED BY LEUKOCYTES | JAPAN ENERGY CORPORATION (JP) | 1997-02-11 | — | — | US | disclosed |
| EP-0675124-A2 | Purine derivatives and suppressants for inflammatory diseases | JAPAN ENERGY CORPORATION (JP) | 1995-10-04 | — | — | EP | disclosed |