Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 8/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008822 | 0.81 | ELANE (0.56) | ELANEAPPCA1CA2CA9 | |
| SCHEMBL9196159 | 0.81 | ACHE (0.41) | ELANECA1CA2CA9 | |
| SCHEMBL21408547 | 0.79 | MEN1 (0.48) | ELANEAPP | |
| SCHEMBL9581834 | 0.79 | MAPT (0.44) | ELANEAPPTRPV1CA1CA2 | |
| SCHEMBL7843630 | 0.79 | ELANE (0.39) | ELANECA1CA2CA9PYCR1 | |
| SCHEMBL17186898 | 0.79 | PPARA (0.48) | ELANE | |
| SCHEMBL8803204 | 0.79 | ELANE (0.42) | ELANETRPV1 | |
| SCHEMBL18405594 | 0.78 | CA4 (0.39) | ELANE | |
| SCHEMBL7768141 | 0.76 | CA1 (0.39) | ELANETRPV1CA1CA2CA9 | |
| SCHEMBL6948975 | 0.76 | KIF11 (0.41) | ELANECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048698-A1 | COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS | ELI LILLY AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
| US-5612323-A | ANTIISCHEMIC | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0401010-B1 | Pyranyl cyanoguanidine derivatives | SQUIBB & SONS INC (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5140031-A | Pyranyl cyanoguanidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0401010-A2 | Pyranyl cyanoguanidine derivatives | E.R. Squibb & Sons, Inc. (US) | 1990-12-05 | — | — | EP | disclosed |
| WO-1990012011-A1 | NOVEL ANTIHYPERTENSIVE BENZOPYRAN DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-10-18 | — | — | WO | disclosed |
| US-4908378-A | Benzopyran derivatives and antihypertensive use thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-03-13 | — | — | US | disclosed |