Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788651 | 0.71 | CHRM1 (0.42) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10789177 | 0.70 | CHRM1 (0.41) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL8901652 | 0.68 | CYP1A2 (0.39) | ADRA1AMAPTALOX15CYP1A2 | |
| SCHEMBL8901847 | 0.68 | CHRM1 (0.41) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL8901942 | 0.67 | SMN1; SMN2 (0.41) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL9755757 | 0.67 | MAPT (0.41) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL10785294 | 0.66 | CHRM1 (0.42) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL10785282 | 0.66 | CHRM1 (0.42) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL11095510 | 0.64 | CHRM1 (0.39) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 | |
| SCHEMBL10862530 | 0.63 | CHRM1 (0.46) | CHRM1TBXA2RPTGS1ADRA1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |