Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901847 | 0.89 | CHRM1 (0.41) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL8901942 | 0.82 | SMN1; SMN2 (0.41) | MAPTALDH1A1KDM4ECYP3A4MAPK1 | |
| SCHEMBL9755776 | 0.76 | MAPT (0.37) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL31745135 | 0.72 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL11291057 | 0.72 | MAPT (0.44) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL497017 | 0.70 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL10789834 | 0.70 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL27321737 | 0.69 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL899150 | 0.68 | MEN1 (0.68) | MAPTMEN1KMT2AALDH1A1MAOA | |
| SCHEMBL10693025 | 0.68 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |