Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901847 | 0.83 | CHRM1 (0.41) | SMN1; SMN2LMNAALDH1A1MAPTMITF | |
| SCHEMBL9755757 | 0.82 | MAPT (0.41) | SMN1; SMN2ALDH1A1MAPTAPAF1MITF | |
| SCHEMBL8901644 | 0.71 | CTDSP1 (0.44) | ALDH1A1ADRA1ACYP1A2TSHRTDP1 | |
| SCHEMBL9755776 | 0.71 | MAPT (0.37) | SMN1; SMN2LMNAALDH1A1MAPTMITF | |
| SCHEMBL8901512 | 0.70 | NQO1 (0.36) | ALDH1A1MAPTCYP1A2CYP2C19MAPK1 | |
| SCHEMBL8903420 | 0.70 | KDM4E (0.35) | SMN1; SMN2LMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL8901797 | 0.70 | KDM4E (0.35) | SMN1; SMN2LMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL21847501 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRGAAKDM4E | |
| SCHEMBL8901951 | 0.67 | CHRM1 (0.38) | SMN1; SMN2LMNAALDH1A1MAPTAPAF1 | |
| SCHEMBL8903879 | 0.67 | KDM4E (0.36) | SMN1; SMN2ALDH1A1MAPTCYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593970-A | ANTITUMOR AND ANTCARCINOGENIC AGENTS; TRETMENT OF CANCEROUS BONE MARROW BEFORE REGRAFTING | BIOCHEM PHARMA INC. (CA) | 1997-01-14 | — | — | US | disclosed |