Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819269 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL2205003 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL29818696 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL29818639 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL2204316 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL4572126 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL2207425 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL20295199 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL29818787 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 | |
| SCHEMBL2205524 | 1.00 | SIRT2 (0.43) | SIRT2PARP10PARP15TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129894-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129894-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | SIRT2 923/4885PARP10 1814/4885PARP15 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.