Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687623 | 0.94 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4685846 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4684785 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4686390 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL10974209 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL679871 | 0.81 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL7812414 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL8621148 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL422519 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL9865701 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5659065-A | CHEMICAL INTERMEDIATES FOR MEDICINAL ACTIVE AGENTS | NOVARTIS CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0678500-A1 | Alpha-amino alkanoic acids and reduction products as intermediates in the preparation of renin inhibitors | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |