Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28967857 | 0.90 | TYR (0.39) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1208161 | 0.87 | TSHR (0.45) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL27667027 | 0.85 | TSHR (0.57) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL1208160 | 0.82 | TYR (0.41) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL29287656 | 0.79 | TSHR (0.53) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL8736185 | 0.78 | TSHR (0.41) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL30026525 | 0.77 | THRB (0.37) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL9160246 | 0.77 | GABRP (0.47) | ALDH1A1HSD17B10TYR | |
| SCHEMBL28858812 | 0.76 | TSHR (0.44) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| SCHEMBL28074918 | 0.75 | TSHR (0.51) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106795662-A | Use of expandable polymer filaments and expanded fabric | 纤科赛尔隆有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-5639546-A | CURED LAYER OF A CROSSLINKED POLYMER MATRIX AND DISPERSED COLLOIDAL METAL OXIDE PARTICLES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0475592-A2 | Coated article having improved adhesion to organic coatings | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |