Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863734 | 0.84 | TDP1 (0.40) | TAAR1GABRA1GABRB2TSHR | |
| SCHEMBL8900885 | 0.83 | TRPA1 (0.50) | TRPA1ATMIAPPHTR1AMAPT | |
| SCHEMBL29217459 | 0.81 | TYR (0.43) | TRPA1ATMMAPTMEN1KMT2A | |
| SCHEMBL1917838 | 0.81 | TRPA1 (0.48) | TRPA1ATMIAPPHTR1AMAPT | |
| SCHEMBL1039776 | 0.81 | TRPA1 (0.48) | TRPA1ATMIAPPHTR1AMAPT | |
| SCHEMBL27622035 | 0.79 | TRPA1 (0.46) | TRPA1ATMIAPPHTR1AMAPT | |
| SCHEMBL29712516 | 0.78 | ESR1 (0.42) | TRPA1ATMMAPTTP53GAA | |
| SCHEMBL10933913 | 0.78 | ESR1 (0.42) | TRPA1ATMMAPTTP53GAA | |
| SCHEMBL29788064 | 0.78 | TAAR1 (0.60) | HTR1AHSPA5TAAR1CYP2D6TSHR | |
| SCHEMBL990719 | 0.78 | TAAR1 (0.60) | HTR1AHSPA5TAAR1CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700897-A | Method for making fluorescent polymers | OPTICAL SENSORS INCORPORATED (US) | 1997-12-23 | — | — | US | disclosed |
| US-5480723-A | Surface-bound fluorescent polymers and related methods of synthesis and use | OPTICAL SENSORS INCORPORATED (US) | 1996-01-02 | — | — | US | disclosed |
| US-5354825-A | Surface-bound fluorescent polymers and related methods of synthesis and use | KLAINER STANLEY M (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1988005533-A1 | AMPLIFICATION OF SIGNALS FROM OPTICAL FIBERS | KELSIUS, INC. (US) | 1988-07-28 | — | — | WO | disclosed |