Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901237 | 0.85 | GAA (0.51) | KDM4EALDH1A1HPGDHSD17B10STING1 | |
| SCHEMBL18203889 | 0.82 | KDM4E (0.48) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL12444067 | 0.82 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL2337780 | 0.81 | HTT (0.51) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1725888 | 0.81 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDNPSR1LCK | |
| Hydrochloric Acid SCHEMBL28599506 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL29765241 | 0.80 | LCK (0.73) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL347214 | 0.80 | LCK (0.73) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL2830233 | 0.80 | LCK (0.72) | KDM4EALDH1A1HPGDNPSR1LCK | |
| Hydrochloric Acid SCHEMBL22129893 | 0.78 | LCK (0.70) | KDM4EALDH1A1HPGDNPSR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |