Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902176 | 0.85 | KDM4E (0.51) | KDM4EKMT2AHPGDSTING1HSD17B10 | |
| SCHEMBL972983 | 0.84 | GAA (0.64) | GAAKDM4EPOLBATMHTT | |
| SCHEMBL8901392 | 0.82 | GAA (0.49) | GAAKDM4EPOLBHTTKMT2A | |
| SCHEMBL7466908 | 0.82 | KDM4E (0.68) | GAAKDM4EPOLBHTTKMT2A | |
| SCHEMBL6582728 | 0.82 | KDM4E (0.67) | GAAKDM4EPOLBHTTKMT2A | |
| SCHEMBL1966436 | 0.81 | GAA (0.59) | GAAKDM4EPOLBATMHTT | |
| SCHEMBL31215241 | 0.81 | GAA (0.59) | GAAKDM4EPOLBATMHTT | |
| SCHEMBL2337975 | 0.81 | HTT (0.67) | GAAKDM4EPOLBHTTKMT2A | |
| SCHEMBL12190698 | 0.79 | CHEK1 (0.47) | GAAKDM4EPOLBHTTHSD17B10 | |
| SCHEMBL18968659 | 0.78 | HTT (0.46) | GAAKDM4EPOLBATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686482-A | DOPAMINE RECEPTOR ANTAGONIST | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0757985-A1 | N-(3-PYRROLIDINYL)BENZAMIDE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |