Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.62 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | THPO | P40225 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622588 | 0.87 | ADORA1 (0.69) | ADORA3SLC29A1DNPH1ADORA2AADORA1 | |
| SCHEMBL1140717 | 0.86 | SLC29A1 (0.64) | ADORA3SLC29A1TP53TDP1DNPH1 | |
| SCHEMBL22458254 | 0.85 | DNPH1 (0.56) | ADORA3SLC29A1TP53TDP1DNPH1 | |
| SCHEMBL21192264 | 0.85 | SLC29A1 (0.62) | ADORA3SLC29A1TP53DNPH1ADORA1 | |
| SCHEMBL19488390 | 0.85 | SLC29A1 (0.62) | ADORA3SLC29A1TP53DNPH1ADORA1 | |
| SCHEMBL472570 | 0.84 | ADORA1 (0.76) | ADORA3SLC29A1ADORA2AADORA1 | |
| SCHEMBL22458248 | 0.82 | ADORA1 (0.65) | ADORA3SLC29A1DNPH1ADORA2AADORA1 | |
| SCHEMBL22458245 | 0.81 | ADORA3 (0.65) | ADORA3SLC29A1TP53TDP1DNPH1 | |
| SCHEMBL13268914 | 0.81 | ADORA3 (0.78) | ADORA3SLC29A1TP53TDP1DNPH1 | |
| SCHEMBL24674538 | 0.81 | ADORA3 (0.72) | ADORA3SLC29A1ADORA2AADORA1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997033879-A1 | COMPOUNDS AND METHODS FOR SELECTIVELY INHIBITING ACTIVATION OF THE HUMAN A3 ADENOSINE RECEPTOR | MERCK & CO., INC. (US) | 1997-09-18 | — | — | WO | disclosed |