SCHEMBL8902811

SCHEMBL8902811

CCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)OCC)cc1

nearest known ligand 0.91

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 10/20 0.77
AGTR2 P50052 10/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026148 0.94 AGTR1 (0.76) AGTR1AGTR2
SCHEMBL7022844 0.94 AGTR1 (0.76) AGTR1AGTR2
SCHEMBL8902733 0.94 AGTR1 (0.68) AGTR1AGTR2
SCHEMBL7026212 0.94 AGTR1 (0.79) AGTR1AGTR2
SCHEMBL8346154 0.93 AGTR1 (0.75) AGTR1AGTR2
SCHEMBL8345878 0.89 AGTR1 (0.78) AGTR1AGTR2
SCHEMBL8970000 0.89 AGTR1 (0.70) AGTR1AGTR2
SCHEMBL9565544 0.89 AGTR2 (0.61) AGTR1AGTR2
SCHEMBL7023527 0.89 AGTR2 (0.63) AGTR1AGTR2
SCHEMBL9565172 0.87 AGTR2 (0.61) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5604251-A Imidazole derivatives with a biphenylsulfonylurea or biphenylsulfonylurethane side chain and their use as angitensin II receptors HOECHST AKTIENGESELLSCHAFT (DE) 1997-02-18 US disclosed