Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203514 | 0.78 | HRH3 (0.61) | KCNH2TSHRSLC6A2SLC6A4ADRA2A | |
| SCHEMBL3157232 | 0.76 | MAPT (0.53) | TSHRSLC6A2SLC6A4LMNABCHE | |
| SCHEMBL16699619 | 0.76 | CNR2 (0.53) | KCNH2TSHRSLC6A2SLC6A4ADRA2A | |
| SCHEMBL9511821 | 0.75 | BCHE (0.51) | KCNH2TSHRSLC6A2SLC6A4ADRA2B | |
| Hydrochloric Acid SCHEMBL16699996 | 0.74 | CNR2 (0.52) | KCNH2TSHRSLC6A2SLC6A4ADRA2A | |
| SCHEMBL24885667 | 0.73 | KDM4E (0.54) | KCNH2SLC6A2SLC6A4ADRA2ALMNA | |
| SCHEMBL21023409 | 0.73 | KCNH2 (0.43) | KCNH2TSHRTP53SLC6A2SLC6A4 | |
| SCHEMBL547420 | 0.73 | TSHR (0.62) | TSHRTP53LMNAHTR2ASIGMAR1 | |
| SCHEMBL798094 | 0.73 | HRH3 (0.58) | KCNH2TSHRTP53SLC6A2SLC6A4 | |
| SCHEMBL29955255 | 0.72 | LPL (0.48) | TSHRLMNABCHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693861-A | Process for preparing solid amine oxides | ALBEMARLE CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0401503-B1 | Solid non-hygroscopic trialkylamine oxides | ALBEMARLE CORP (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5292954-A | Amine oxide composition and process | ETHYL CORPORATION (US) | 1994-03-08 | — | — | US | disclosed |
| US-5254735-A | Process for preparing solid amine oxides | ETHYL CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| US-5208374-A | Oxidation of a tertiary amine with hydrogen peroxide | ETHYL CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530314-A1 | AMINE OXIDE COMPOSITION AND PROCESS. | ETHYL CORP (US) | 1993-03-10 | — | — | EP | disclosed |
| EP-0426084-B1 | AMINE OXIDE PROCESS | ETHYL CORPORATION (US) | 1993-01-27 | — | — | EP | disclosed |
| US-5164121-A | Pourable composition containing an amine oxide -polyethylene glycol mixture | ETHYL CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| US-5120469-A | Amine oxide composition and process | ETHYL CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| WO-1991018079-A1 | AMINE OXIDE COMPOSITION AND PROCESS | ETHYL CORPORATION (US) | 1991-11-28 | — | — | WO | disclosed |
| US-5068430-A | Bleaching of colored amine oxides | ETHYL CORPORATION (US) | 1991-11-26 | — | — | US | disclosed |
| US-5055232-A | Pourable liquid blend of amine oxide and nonionic surfactant | ETHYL CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| US-5055614-A | Amine oxide composition and process | ETHYL CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0426084-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1991-05-08 | — | — | EP | disclosed |
| EP-0424965-A1 | Amine oxide process | ETHYL CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0401503-A2 | Solid non-hygroscopic trialkylamine oxides | ALBEMARLE CORPORATION (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4960934-A | Amine oxide process | ETHYL CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |