Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037591 | 0.79 | NR4A2 (0.44) | TP53TSHRLMNASIGMAR1EPHX1 | |
| SCHEMBL7037587 | 0.79 | NR4A2 (0.44) | TP53TSHRLMNASIGMAR1EPHX1 | |
| SCHEMBL13995227 | 0.78 | ADRA2B (0.69) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B | |
| SCHEMBL13995599 | 0.78 | ADRA2B (0.69) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B | |
| SCHEMBL13995597 | 0.78 | ADRA2B (0.69) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B | |
| SCHEMBL7369137 | 0.74 | MEN1 (0.38) | TP53TSHRLMNAALDH1A1EPHX1 | |
| SCHEMBL7369135 | 0.74 | MEN1 (0.38) | TP53TSHRLMNAALDH1A1EPHX1 | |
| SCHEMBL798094 | 0.73 | HRH3 (0.58) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B | |
| SCHEMBL8902822 | 0.73 | KCNH2 (0.44) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B | |
| SCHEMBL8053786 | 0.71 | KCNH2 (0.46) | KCNH2SLC6A2HTR2ASLC6A4ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485881-A1 | PERMANENTLY CHARGED SODIUM AND CALCIUM CHANNEL BLOCKERS AS ANTI-INFLAMMATORY AGENTS | President and Fellows of Harvard College (US) | 2019-05-22 | — | — | EP | disclosed |