Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903081 | 0.97 | ITGB3 (0.36) | ITGB3ITGB1ITGAVITGA4HDAC1 | |
| SCHEMBL10702630 | 0.88 | HDAC1 (0.32) | ITGB3ITGB1ITGAVITGA4HDAC1 | |
| SCHEMBL8903294 | 0.78 | CRBN (0.32) | ITGB3ITGB1ITGAVITGA4CRBN | |
| SCHEMBL7538005 | 0.69 | MGLL (0.32) | — | |
| SCHEMBL6291060 | 0.66 | HDAC1 (0.44) | HDAC1CTSK | |
| SCHEMBL17866752 | 0.66 | HDAC1 (0.44) | HDAC1CTSK | |
| SCHEMBL4909784 | 0.64 | ITGB3 (0.32) | ITGB3ITGB1ITGAVITGA4 | |
| SCHEMBL24471489 | 0.61 | — | — | |
| Succinimide SCHEMBL6717091 | 0.59 | CRBN (0.73) | ITGB3ITGB1ITGAVITGA4CRBN | |
| Succinimide SCHEMBL6036901 | 0.59 | CRBN (0.73) | ITGB3ITGB1ITGAVITGA4CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633243-A | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5527905-A | RELATIVELY FEW SIDE EFFECTS, GOOD SOLUBILITY IN WATER | SANKYO COMPANY, LIMITED (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0290280-B1 | Anti-tumor platinum complexes, their preparation and their therapeutic use | SANKYO CO (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0290280-A2 | Anti-tumor platinum complexes, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1988-11-09 | — | — | EP | disclosed |