Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13016543 | 0.94 | CYP1A2 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL16952926 | 0.89 | MCHR1 (0.40) | MAPTMCHR1CNR1CNR2L3MBTL1 | |
| SCHEMBL8903543 | 0.84 | MCHR1 (0.43) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL4826935 | 0.83 | L3MBTL1 (0.54) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL8234319 | 0.83 | L3MBTL1 (0.54) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10383341 | 0.83 | MAPT (0.55) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10427831 | 0.83 | MAPT (0.55) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL13443129 | 0.83 | MAPT (0.55) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL10430491 | 0.83 | MAPT (0.55) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL7781687 | 0.83 | L3MBTL1 (0.54) | MEN1NR1I2LMNACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648021-A | Phenanthrene derivatives and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |