SCHEMBL16952926

SCHEMBL16952926

CCCOc1cccc(CO)c1F

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.40
CYP2A6 P11509 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2D6 P10635 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PDE4D Q08499 1/20 0.36
HTR1B P28222 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
CYP2C9 P11712 1/20 0.36
HTR1D P28221 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13016543 0.92 CYP1A2 (0.46) MCHR1L3MBTL1MAPTCNR1CNR2
SCHEMBL8903015 0.89 MEN1 (0.47) MCHR1L3MBTL1MAPTCNR1CNR2
SCHEMBL16957186 0.86 ALDH1A1 (0.45) L3MBTL1MAPTNPSR1CYP1A2CYP2C19
SCHEMBL16958644 0.85 L3MBTL1 (0.38) L3MBTL1MAPTNPSR1CYP1A2CYP2C19
SCHEMBL7216512 0.82 MAPT (0.52) CYP2A6L3MBTL1MAPTNPSR1CNR1
SCHEMBL8216509 0.82 L3MBTL1 (0.50) MCHR1CYP2A6L3MBTL1MAPTCYP1A2
SCHEMBL16955136 0.81 PDCD1 (0.44) MCHR1CYP2A6L3MBTL1MAPTNPSR1
SCHEMBL16962193 0.79 MCHR1 (0.40) MCHR1CYP2A6L3MBTL1MAPTNPSR1
SCHEMBL16962845 0.79 MAPT (0.42) MCHR1CYP2A6L3MBTL1MAPTNPSR1
SCHEMBL7574010 0.79 CNR1 (0.41) MCHR1CYP2A6L3MBTL1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed