Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.52 |
| ▸ | RARB | P10826 | 17/20 | 0.52 |
| ▸ | RARG | P13631 | 17/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772613 | 0.88 | RARA (0.52) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8902592 | 0.87 | RARA (0.67) | RARARARBRARGCYP3A4 | |
| SCHEMBL7805699 | 0.85 | RARA (0.60) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6420934 | 0.85 | RARA (0.49) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL6240831 | 0.83 | RARA (0.76) | RARARARBRARG | |
| SCHEMBL7641992 | 0.82 | RARA (0.56) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL7639318 | 0.81 | RARA (0.53) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8772596 | 0.80 | RARA (0.52) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL8683642 | 0.80 | RARA (0.57) | RARARARBRARGCYP3A4KMT2A | |
| SCHEMBL6236965 | 0.80 | RARA (0.76) | RARARARBRARGCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618931-A | SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | ALLERGAN | 1997-04-08 | — | — | US | disclosed |
| WO-1996020930-A1 | ACETYLENES DISUBSTITUTED WITH A 5 OR 8 SUBSTITUTED TETRAHYDRONAPHTHYL OR DIHYDRONAPHTHYL GROUP AND WITH AN ARYL OR HETEROARYL GROUPS HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN (US) | 1996-07-11 | — | — | WO | disclosed |