Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902891 | 0.86 | MEN1 (0.31) | HSD17B10MEN1KMT2A | |
| SCHEMBL7520417 | 0.75 | TDP1 (0.46) | HSD17B10KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7786427 | 0.73 | RXRB (0.49) | HSD17B10NOTUMRXRBKDM4EALDH1A1 | |
| SCHEMBL1434189 | 0.72 | HSD17B10 (0.52) | HSD17B10NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL9187455 | 0.72 | RXRB (0.47) | HSD17B10NOTUMRXRBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7945358 | 0.72 | TDP1 (0.44) | HSD17B10NOTUMRXRBKDM4EMAPT | |
| SCHEMBL10920134 | 0.71 | KDM4E (0.55) | HSD17B10NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL4339765 | 0.71 | ALDH1A1 (0.36) | HSD17B10NOTUMKDM4EALDH1A1TDP1 | |
| SCHEMBL9191019 | 0.70 | KDM4E (0.53) | HSD17B10NOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL27481246 | 0.70 | HSD17B10 (0.49) | HSD17B10KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607625-A | TEST KITS CONTAINING THE DIOXETANES | ABBOTT LABORATORIES (US) | 1997-03-04 | — | — | US | disclosed |