Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346992 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL1562131 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL9221220 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL27391923 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL4121004 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL4121000 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HTTGAAHPGDKDM4E | |
| SCHEMBL8904797 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HTTGAATDP1PPARG | |
| SCHEMBL1561567 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HTTGAAPPARGPPARA | |
| SCHEMBL8904838 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HTTGAAPPARGPPARA | |
| SCHEMBL8904841 | 0.87 | ALDH1A1 (0.40) | ALDH1A1HTTGAAPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618808-A | Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists | PFIZER, INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0648213-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001421-A1 | BENZOTHIAZEPINE AND BENZOXAZEPINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1994-01-20 | — | — | WO | disclosed |