Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | DHFR | P00374 | 6/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429787 | 0.89 | CYP2D6 (0.71) | CYP2D6DHFRMAOB | |
| SCHEMBL6347041 | 0.79 | DHFR (0.74) | CYP2D6DHFR | |
| SCHEMBL27084609 | 0.79 | CYP2D6 (0.75) | CYP2D6DHFRTLR8TLR7 | |
| SCHEMBL6667212 | 0.77 | CYP2D6 (0.79) | CYP2D6DHFRTLR8TLR7MAOB | |
| SCHEMBL4847314 | 0.76 | DHFR (0.69) | CYP2D6DHFR | |
| SCHEMBL17545030 | 0.74 | DHFR (0.54) | CYP2D6DHFRTLR8TLR7 | |
| SCHEMBL6344234 | 0.74 | CYP2D6 (0.67) | CYP2D6DHFRTLR8TLR7MAOB | |
| SCHEMBL8903398 | 0.74 | DHFR (0.59) | CYP2D6DHFR | |
| SCHEMBL6342295 | 0.73 | DHFR (0.60) | CYP2D6DHFR | |
| SCHEMBL29354447 | 0.72 | DHFR (0.56) | CYP2D6DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627189-A | Insecticidal 5-substituted-2,4-diaminopyrimidine derivatives | FMC CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| US-5587379-A | CONTROLLING INSECTS IN AGRICULTURAL CROPS | FMC CORPORATION (US) | 1996-12-24 | — | — | US | disclosed |
| US-5521192-A | TOBACCO BUDWORM, CABBAGE LOOPER, BEET ARMYWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0671881-A4 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES. | FMC CORP (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0671881-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012032-A1 | INSECTICIDAL 5-SUBSTITUTED-2,4-DIAMINOPYRIMIDINE DERIVATIVES | FMC CORPORATION (US) | 1994-06-09 | — | — | WO | disclosed |