Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902714 | 0.90 | GAA (0.50) | GAATSHRNPSR1SIGMAR1TDP1 | |
| SCHEMBL8902528 | 0.86 | GAA (0.48) | GAATSHRNPSR1SIGMAR1TDP1 | |
| SCHEMBL8902235 | 0.82 | NPY5R (0.56) | GAATSHRNPSR1SIGMAR1NPY5R | |
| SCHEMBL8893932 | 0.79 | NPY5R (0.51) | GAATSHRNPSR1TDP1NPY5R | |
| SCHEMBL8902755 | 0.78 | NPY5R (0.43) | GAATSHRNPSR1SIGMAR1TDP1 | |
| Hydrochloric Acid SCHEMBL8893467 | 0.77 | TMEM97 (0.47) | GAATSHRNPSR1NPY5R | |
| Hydrochloric Acid SCHEMBL8902347 | 0.77 | NPY5R (0.44) | GAATSHRNPSR1SIGMAR1TDP1 | |
| SCHEMBL13696444 | 0.76 | NPY5R (0.61) | GAATSHRNPSR1TDP1NPY5R | |
| Tiaramide SCHEMBL25172 | 0.74 | NPY5R (0.58) | GAATSHRNPSR1NPY5R | |
| Tiaramide SCHEMBL29376518 | 0.74 | NPY5R (0.58) | GAATSHRNPSR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |