SCHEMBL8903644

SCHEMBL8903644

CCC1CCC(OC(=O)Cl)CC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.47
EPHX1 P07099 1/20 0.36
NAAA Q02083 3/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
ENPP2 Q13822 2/20 0.32
EPHX2 P34913 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
ADRA1A P35348 1/20 0.30
CHRNA4 P43681 1/20 0.30
HTR3A P46098 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11006105 0.84 NAAA (0.40) CYP19A1EPHX1NAAANPC1MAPT
SCHEMBL8904486 0.84 NAAA (0.40) CYP19A1EPHX1NAAANPC1MAPT
SCHEMBL11469820 0.83 CYP19A1 (0.33) CYP19A1EPHX1CHRM2CHRM1CHRM3
SCHEMBL11422188 0.82 SERPINE1 (0.37) EPHX1NAAA
SCHEMBL9275379 0.82 SERPINE1 (0.37) EPHX1NAAA
SCHEMBL221501 0.82
SCHEMBL11423412 0.82 SERPINE1 (0.37) EPHX1NAAA
SCHEMBL8903306 0.81 NAAA (0.51) CYP19A1NAAAMEN1MAPTKMT2A
SCHEMBL20289703 0.81 CYP19A1 (0.50) CYP19A1EPHX1NAAAMEN1NPC1
SCHEMBL15712634 0.81 CYP19A1 (0.49) CYP19A1EPHX1NAAAMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5656198-A DISPLAY DEVICE CITIZEN WATCH CO., LTD. (JP) 1997-08-12 US disclosed