Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367114 | 0.86 | IGF1R (0.46) | LMNASMN1; SMN2ESR1CYP19A1ESR2 | |
| SCHEMBL18917599 | 0.83 | IGF1R (0.40) | NPC1RAB9ASMN1; SMN2ESR1CYP19A1 | |
| SCHEMBL10372347 | 0.82 | CALM1 (0.47) | LMNAMAPTRAB9ASMN1; SMN2CALM1 | |
| SCHEMBL7028563 | 0.82 | IGF1R (0.42) | KDM4ENPC1CYP1A2CYP3A4MAPT | |
| SCHEMBL5679284 | 0.81 | IDH1 (0.44) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7025423 | 0.81 | CTDSP1 (0.45) | LMNACYP1A2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30723203 | 0.80 | GAA (0.39) | KDM4ELMNACYP3A4MAPTESR2 | |
| SCHEMBL816601 | 0.80 | GAA (0.39) | KDM4ELMNACYP3A4MAPTESR2 | |
| SCHEMBL18917603 | 0.79 | TDP1 (0.40) | NPC1RAB9ASMN1; SMN2CYP19A1AKR1C3 | |
| SCHEMBL5950230 | 0.79 | CHRM2 (0.47) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860169-B1 | Method for obtaining novel derivatives of naphtalene for the in vivo diagnosis of Alzheimer's disease | CENTRO DE NEUROCIENCIAS DE CUBA (CU) | 2018-08-29 | — | — | EP | disclosed |
| EP-2860169-A2 | Method for obtaining novel derivatives of naphtalene for the in vivo diagnosis of Alzheimer's disease | Centro De Neurociencias De Cuba (CU) | 2015-04-15 | — | — | EP | disclosed |
| EP-2436666-A2 | METHOD FOR OBTAINING NOVEL DERIVATIVES OF NAPHTALENE FOR THE IN VIVO DIAGNOSIS OF ALZHEIMER 'S DISEASE | Centro De Neurociencias De Cuba (CU) | 2012-04-04 | — | — | EP | disclosed |