SCHEMBL8903998

SCHEMBL8903998

C=CC(=O)C(C)OOC(=O)CCC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.36
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
TSHR P16473 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 2/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
SUCNR1 Q9BXA5 1/20 0.31
GABRP O00591 2/20 0.31
GABRD O14764 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903995 0.93 TSHR (0.35) TSHR
SCHEMBL29204382 0.80 KDM6B (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL29204383 0.80 KDM6B (0.34) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL8996644 0.80 EGLN1 (0.42) EGLN1KDM6BKDM5CPHF8KDM2A
Ammonia Solution, Strong SCHEMBL11412535 0.78 EGLN1 (0.41) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL2407817 0.76 EGLN1 (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL10877080 0.75 EGLN1 (0.45) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL11548672 0.74 GABRP (0.39) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL8996634 0.73 TSHR (0.36) EGLN1KDM6BKDM5CPHF8KDM2A
SCHEMBL301338 0.70 LMNA (0.39) EGLN1KDM6BKDM5CPHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654348-A FIBER IMPREGNATED WITH ALCOHOL OR GLYCOL ACRYLATE OR METHACRYLATE, GLYCOL DIGLYCIDYL ETHER, TREATED WITH ULTRAVIOLET RADIATION KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 1997-08-05 US disclosed