Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28807882 | 0.98 | GRIK1 (0.59) | GRIK1PTGESALOX5PPARGCNR2 | |
| SCHEMBL8904462 | 0.98 | GRIK1 (0.59) | GRIK1PTGESALOX5PPARGCNR2 | |
| SCHEMBL30839920 | 0.95 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL355603 | 0.95 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL10869949 | 0.95 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL11305180 | 0.95 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL5385323 | 0.95 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL1131425 | 0.95 | GRIK1 (0.62) | GRIK1PTGESALOX5PPARGCNR2 | |
| SCHEMBL8904812 | 0.93 | MMP2 (0.56) | GRIK1PTGESALOX5PPARGCNR2 | |
| SCHEMBL8905261 | 0.92 | MMP2 (0.55) | GRIK1PTGESALOX5PPARGCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206866-A | Prostaglandin E2Receptor 4 antagonists and uses thereof | 泰昂治疗公司 | 2022-03-18 | — | — | CN | disclosed |
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |