Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 3/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | RARB | P10826 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839920 | 1.00 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL10869949 | 1.00 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL5385323 | 1.00 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL11305180 | 1.00 | GRIK1 (0.55) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL28807882 | 0.97 | GRIK1 (0.59) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL8845872 | 0.97 | PTGES (0.56) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL8904462 | 0.97 | GRIK1 (0.59) | GRIK1PTGESALOX5PPARGS1PR2 | |
| SCHEMBL8845789 | 0.97 | PTGES (0.56) | GRIK1PTGESALOX5PPARGCPB2 | |
| SCHEMBL8904064 | 0.95 | GRIK1 (0.60) | GRIK1PTGESALOX5PPARGALDH1A1 | |
| SCHEMBL8905261 | 0.94 | MMP2 (0.55) | GRIK1PTGESALOX5PPARGS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2707470-B1 | AROMATIC IMIDES AS LUBRICANT ADDITIVES | LUBRIZOL CORP (US) | 2021-04-21 | — | — | EP | disclosed |
| EP-2398873-B1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2430134-B1 | METHOD USING IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9006156-B2 | Imides and bis-imides as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2015-04-14 | — | — | US | disclosed |
| EP-2398876-B1 | OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2014-11-19 | — | — | EP | disclosed |
| US-8778858-B2 | Amine derivatives as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2014-07-15 | — | — | US | disclosed |
| EP-2707470-A1 | AROMATIC IMIDES AND ESTERS AS LUBRICANT ADDITIVES | The Lubrizol Corporation (US) | 2014-03-19 | — | — | EP | disclosed |
| EP-2406358-B1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | LUBRIZOL CORP (US) | 2013-08-21 | — | — | EP | disclosed |
| US-8501674-B2 | Amine derivatives as friction modifiers in lubricants | THE LUBRIZOL CORPORATION (US) | 2013-08-06 | — | — | US | disclosed |
| WO-2012154708-A1 | AROMATIC IMIDES AND ESTERS AS LUBRICANT ADDITIVES | THE LUBRIZOL CORPORATION (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2430134-A1 | IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | The Lubrizol Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20120021958-A1 | Oxalic Acid Bis-Amides or Amide-Ester as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120015855-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION | 2012-01-19 | — | — | US | disclosed |
| EP-2406358-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | The Lubrizol Corporation (US) | 2012-01-18 | — | — | EP | disclosed |
| EP-2398873-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | The Lubrizol Corporation (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010132318-A1 | IMIDES AND BIS-AMIDES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010096325-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096321-A1 | OXALIC ACID BIS-AMIDES OR AMIDE-ESTER AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096318-A1 | AMINE DERIVATIVES AS FRICTION MODIFIERS IN LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |
| US-20100210490-A1 | Amine Derivatives as Friction Modifiers in Lubricants | THE LUBRIZOL CORPORATION (US) | 2010-08-19 | — | — | US | disclosed |