Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904646 | 0.85 | MAPT (0.32) | MAPTTSHRHTTHSD17B10ALDH1A1 | |
| SCHEMBL16943741 | 0.84 | ELANE (0.32) | ALDH1A1 | |
| SCHEMBL8905763 | 0.83 | GAA (0.32) | MAPTTSHRHTTALDH1A1 | |
| SCHEMBL8904127 | 0.82 | KMT2A (0.36) | MAPTTSHRHTTALDH1A1LMNA | |
| SCHEMBL16943745 | 0.80 | — | — | |
| SCHEMBL8905714 | 0.80 | ALDH1A1 (0.35) | MAPTTSHRHTTALDH1A1ALOX15 | |
| SCHEMBL8905724 | 0.80 | — | — | |
| SCHEMBL8905063 | 0.80 | RECQL (0.38) | MAPTPTPN1ACP1CDC25B | |
| SCHEMBL8905920 | 0.79 | PRKCA (0.39) | MAPTPTPN1ACP1CDC25B | |
| SCHEMBL8904855 | 0.77 | PRKCA (0.41) | MAPTPTPN1ACP1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698585-A | FOR SENILE CATARACT CAUSED BY OXIDATION DISORDER; VISION DEFECTS | KIKKOMAN CORPORATION (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0737476-A2 | A pharmaceutical preparation containing a 3-(2H)-furanone derivative for prevention and/or treatment of cataracts | KIKKOMAN CORPORATION (JP) | 1996-10-16 | — | — | EP | disclosed |