Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 9/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272417 | 0.79 | ALDH1A1 (0.66) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL8904144 | 0.78 | HDAC1 (0.43) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL10996722 | 0.77 | HDAC1 (0.47) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL9583145 | 0.75 | MEN1 (0.62) | HDAC1HSP90AB1HSP90AA1HDAC6HDAC4 | |
| SCHEMBL9776572 | 0.74 | HDAC6 (0.49) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL14477480 | 0.74 | HDAC6 (0.51) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL10510295 | 0.72 | HDAC1 (0.44) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL15788021 | 0.72 | HDAC6 (0.46) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL7617492 | 0.71 | HDAC1 (0.45) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 | |
| SCHEMBL8708630 | 0.71 | HDAC1 (0.43) | HDAC1HDAC2HSP90AB1HSP90AA1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |