1-Naphthol

1-Naphthol

SCHEMBL8904232

Oc1cccc2ccccc12.c1ccc2ccccc2c1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.94
IDO1 P14902 1/20 0.55
PTPN22 Q9Y2R2 1/20 0.54
HSD17B10 Q99714 5/20 0.52
TDP1 Q9NUW8 3/20 0.52
TSHR P16473 3/20 0.52
HPGD P15428 3/20 0.52
MAPT P10636 2/20 0.52
ALOX15 P16050 2/20 0.52
RECQL P46063 2/20 0.52
APP P05067 1/20 0.52
THRB P10828 1/20 0.52
CASP1 P29466 1/20 0.52
SNCA P37840 1/20 0.52
NQO2 P16083 1/20 0.52
KDM4E B2RXH2 2/20 0.52
PLAU P00749 1/20 0.52
MAPKAPK2 P49137 1/20 0.52
CTDSP1 Q9GZU7 1/20 0.52
ALDH1A1 P00352 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL10486461 0.97 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL3416 0.97 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL29767730 0.97 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL273260 0.97 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL8219136 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL11295882 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL9850314 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL3924043 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL21490911 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL9850309 0.94 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101172964-A 3-(4-piperidine group) substituted tetrahydronaphthalene derivative compounds and synthesis method thereof JIEDAWEI SHANGHAI MEDICAL TECH (CN) 2008-05-07 CN claimed
CN-1539733-A Silicon dioxide composite material containing media pores in concentric ring shaped or in hexagonal structure, and preparation method 中国科学院上海硅酸盐研究所 2004-10-27 CN claimed
US-5620872-A FORMING STARCH HYDROLYZATE; SUBJECTING TO ENZYME TO PRODUCTCYCLODEXTRIN AMERICAN MAIZE-PRODUCTS COMPANY (US) 1997-04-15 US claimed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
CN-110240885-B Resin composition, sheet-like laminate, printed wiring board, and semiconductor device 味之素株式会社 2023-05-02 CN disclosed
CN-111788181-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-01-17 CN disclosed
CN-110527398-B Active energy ray-curable composition 信越化学工业株式会社 2023-01-03 CN disclosed
CN-113264856-B Sulfonium salt, photoacid generator, and photosensitive composition 东京应化工业株式会社 2022-11-22 CN disclosed
CN-114901638-A Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2022-08-12 CN disclosed
CN-114402260-A Photoacid generators 三亚普罗股份有限公司 2022-04-26 CN disclosed
CN-107074759-B Sulfonium salt, photoacid generator, and photosensitive composition 东京应化工业株式会社 2021-12-14 CN disclosed
CN-111788181-A Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2020-10-16 CN disclosed
US-10711088-B2 Resin composition, sheet-shaped laminated material, printed wiring board, and semiconductor device AJINOMOTO CO., INC. (JP) 2020-07-14 US disclosed
US-20190276585-A1 RESIN COMPOSITION, SHEET-SHAPED LAMINATED MATERIAL, PRINTED WIRING BOARD, AND SEMICONDUCTOR DEVICE AJINOMOTO CO., INC. (JP) 2019-09-12 US disclosed
EP-3377612-A1 FUNCTIONAL EXPRESSION OF MONOOXYGENASES AND METHODS OF USE Industrial Microbes, Inc. (US) 2018-09-26 EP disclosed
CN-104781707-B Polarization plate DIC株式会社 2017-05-24 CN disclosed
US-4151174-A 1:1 Adducts of indole and (na)phthalaldehydic acid POLAROID CORPORATION (US) 1979-04-24 US disclosed
US-4115216-A QUARTERNARY AMMONIUM COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-4036863-A Trinapthylmethane compounds POLAROID CORPORATION (US) 1977-07-19 US disclosed
US-3976662-A 1:1 Adducts of 1-naphthol and (Na)phthalaldehydic acid POLAROID CORPORATION (US) 1976-08-24 US disclosed