Sugi Predict

Sugi Predict / Compounds / 1-Naphthol

1-Naphthol

1-Naphthol

SCHEMBL273260

Oc1cccc2ccccc12.Oc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 1.00
▸ IDO1 P14902 1/20 0.58
▸ PTPN22 Q9Y2R2 1/20 0.56
▸ HSD17B10 Q99714 5/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ TSHR P16473 3/20 0.55
▸ HPGD P15428 3/20 0.55
▸ MAPT P10636 2/20 0.55
▸ ALOX15 P16050 2/20 0.55
▸ RECQL P46063 2/20 0.55
▸ APP P05067 1/20 0.55
▸ THRB P10828 1/20 0.55
▸ CASP1 P29466 1/20 0.55
▸ SNCA P37840 1/20 0.55
▸ NQO2 P16083 1/20 0.54
▸ KDM4E B2RXH2 2/20 0.54
▸ PLAU P00749 1/20 0.54
▸ MAPKAPK2 P49137 1/20 0.54
▸ CTDSP1 Q9GZU7 1/20 0.54
▸ ALDH1A1 P00352 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL29767730 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL3416 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL10486461 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL9850309 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL3924043 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL8219136 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL11295882 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL21490911 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL4196679 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL11247168 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101466679-A Process for preparing tetrahydroquinoline derivatives MITSUBISHI TANABE PHARMA CORP (JP) 2009-06-24 — — CN claimed
EP-0610920-B1 Method of preparing naphthol-modified phenolic resin and epoxy resin molding material for sealing electronic parts HITACHI CHEMICAL CO LTD (JP) 1998-04-29 — — EP claimed
EP-0512519-B1 Method of producing naphthol-modified phenolic resin HITACHI CHEMICAL CO LTD (JP) 1997-03-12 — — EP claimed
US-12473283-B2 Compounds and their use DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-11-18 — — US disclosed
US-20240287250-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-08-29 — — US disclosed
EP-4361196-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-05-01 — — EP disclosed
CN-115716912-B Yellowing-resistant thermoplastic resin composition and preparation method and application thereof 万华化学集团股份有限公司 2023-09-19 — — CN disclosed
CN-116375999-A Thermoplastic resin composition, method for producing same, and optical lens 万华化学集团股份有限公司 2023-07-04 — — CN disclosed
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE DEBIOPHARM INTERNATIONAL S.A. (CH) 2023-05-25 — — US disclosed
CN-115926135-A Thermoplastic resin composition for optical forming body and manufacturing method thereof 万华化学集团股份有限公司 2023-04-07 — — CN disclosed
CN-115716912-A Anti-yellowing thermoplastic resin composition and preparation method and application thereof 万华化学集团股份有限公司 2023-02-28 — — CN disclosed
WO-2002004466-A2 CATALYST FOR ASYMMETRIC (TRANSFER) HYDROGENATION DSM N.V. (NL) 2002-01-17 — — WO disclosed
US-20010023302-A1 Process for producing optically active hemiesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-20 — — US disclosed
EP-1092729-A1 POLYMERIZATION CATALYST, NOVEL TRANSITION METAL COMPOUND, AND POLYMERIZATION METHOD AND COPOLYMER USING THEM Mitsui Chemicals, Inc. (JP) 2001-04-18 — — EP disclosed
WO-1996021507-A1 CATALYST FOR ASYMMETRIC DIELS-ALDER REACTIONS ALBEMARLE CORPORATION (US) 1996-07-18 — — WO disclosed
EP-0241235-B1 PROCESS FOR THE PREPARATION OF HOMOALLYL ALCOHOLS ICI AUSTRALIA LIMITED (AU) 1991-02-27 — — EP disclosed
US-4933511-A ORGANOMETALLIC CATALYSTS ICI AUSTRALIA LIMITED (AU) 1990-06-12 — — US disclosed
EP-0297583-A2 Photosensitive material and image forming method by use thereof CANON KABUSHIKI KAISHA (JP) 1989-01-04 — — EP disclosed
EP-0241235-A2 Process for the preparation of homoallyl alcohols ICI AUSTRALIA LIMITED (AU) 1987-10-14 — — EP disclosed
US-3966620-A ALKENYLSUCCINIC ACID OR ANHYDRIDE AND TRISHYDROXYMETHYLAMINOMETHANE REACTION PRODUCT, BI-NAPHTHOL MOBIL OIL CORPORATION (US) 1976-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159519-A1 NOVEL COMPOUNDS AND THEIR USE LSS, PGLS, LDHB CYP1A2 2977/4885IDO1 3837/4885PTPN22 1689/4885
US-20010023302-A1 Process for producing optically active hemiesters ALDH1A2, CYP8B1, HCCS CYP1A2 8/4885IDO1 1705/4885PTPN22 4592/4885
US-12473283-B2 Compounds and their use LSS, PGLS, LDHB CYP1A2 2945/4885IDO1 3550/4885PTPN22 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.