1-Naphthol

1-Naphthol

SCHEMBL3416

Oc1cccc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 1.00
IDO1 P14902 1/20 0.58
PTPN22 Q9Y2R2 1/20 0.56
HSD17B10 Q99714 5/20 0.55
TDP1 Q9NUW8 3/20 0.55
TSHR P16473 3/20 0.55
HPGD P15428 3/20 0.55
MAPT P10636 2/20 0.55
ALOX15 P16050 2/20 0.55
RECQL P46063 2/20 0.55
APP P05067 1/20 0.55
THRB P10828 1/20 0.55
CASP1 P29466 1/20 0.55
SNCA P37840 1/20 0.55
NQO2 P16083 1/20 0.54
KDM4E B2RXH2 2/20 0.54
PLAU P00749 1/20 0.54
MAPKAPK2 P49137 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
ALDH1A1 P00352 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL29767730 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL273260 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL10486461 1.00 CYP1A2 (1.00) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL9850309 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL3924043 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL8219136 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL11295882 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL21490911 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL4196679 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1
1-Naphthol SCHEMBL11247168 0.97 CYP1A2 (0.94) CYP1A2IDO1PTPN22HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 146122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432995-B1 None US claimed
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
CN-122080793-A UV delay curing adhesive, preparation method and application thereof 2026-05-26 CN claimed
US-12636241-B1 Method and composition for oxidative hair coloring WELLA OPERATIONS US LLC (US) 2026-05-26 US claimed
CN-117024681-B Synthesis method of active ester curing agent DONGYING HEBANG CHEMICAL Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122084700-A Hydrogen sensor based on nano particles and preparation method and application thereof 2026-05-26 CN claimed
CN-122080827-A Adhesive film composition for reworking backing plate and preparation method thereof 2026-05-26 CN claimed
CN-122077251-A Lead-free halogen-free soldering paste for QFN device and preparation method thereof 2026-05-26 CN claimed
CN-122078011-A Ultrathin back drill pad plate and preparation method thereof, circuit board and preparation method thereof 2026-05-26 CN claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
US-3934975-A Leather treating process DIAMOND SHAMROCK CORPORATION (US) 1976-01-27 US claimed
US-3935015-A Silver halide color photographic materials containing 3-anilino-5-pyrazolane couplers FUJI PHOTO FILM CO., LTD. (JA) 1976-01-27 US claimed
US-3933500-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US claimed
US-3932189-A Thermodevelopable photographic material containing high silver ion conducting substance FUJI PHOTO FILM CO., LTD. (JA) 1976-01-13 US claimed
US-3932400-A CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-01-13 US claimed
US-3931255-A REDUCING OXIME, IRON(2) IONS AND HYDROGEN HALIDE, OXIDIZING THE NAPHTHOL BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed
US-3930866-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed
US-3931228-A Process for preparing phthalide and naphthalide indicator dyes POLAROID CORPORATION (US) 1976-01-06 US claimed
US-3930863-A MULTILAYER, HYDROQUINONE DERIVATIVES FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed